Premier CoQ-10 contains natural, fat-soluble ubiquinone. It is a product of choice when selecting a CoQ-10 dietary supplement for several important reasons. This CoQ-10 is produced through a natural fermentation process which yields 100 mg/capsule of the bioavailable, preferred trans isomeric form of CoQ-10 (not the less desirable cis isomer form). This process does not use polysorbate 80 (an emulsifier made from polyethoxylated sorbitan), undesirable flowing agents or other excipients. The natural trans isomer of CoQ-10 is the most desirable because it is identical to the CoQ-10 produced by the cells in the body. CoQ-10 is found in the highest concentrations in body tissues with the highest rate of metabolic activity and energy demands (such as in the heart, muscle, liver, kidney and brain).
Is water-soluble ubiquinol really a preferred form?
As a supplement, CoQ-10 can be found in the marketplace as oxidized ubiquinone or reduced ubiquinol (in an assortment of liposmal, micelle and nanoparticle forms). These forms are converted from the oxidized to the reduced form of CoQ-10 and vice versa as needed by the body. Since reduced
ubiquinol is highly unstable, it is readily converted to oxidized ubiquinone in the presence of oxygen, light and an acid media such as hydrochloric acid produced by the stomach. Further, reducing CoQ-10 to a nanoparticle such as CoQ-9, 8 or 7 by cutting off its lipophilic tail, is not a natural process. Although it does become more water soluble, the natural CoQ10 molecule has been
lost. Ubiquinol products in the liposomal, micelle or nanoparticle form are water-soluble microspheres that can rapidly disperse in water, but this does
not enhance the absorption of this altered form of CoQ-10 in the intestines. For best performance, the CoQ-10 molecule must be absorbed by the intestines in its complete lipid form, its true fat-soluble form, for optimal nutrition.
Thus, the preferred form of CoQ-10 is one that is in its natural, original form. Premier CoQ-10 offers live-source CoQ-10 (ubiquinone) that is derived from natural fermentation which is in its natural, original form. In contrast, the more expensive, water-soluble form of CoQ-10 as ubiquinol has been altered to make it more water soluble. When this unnatural form of CoQ-10 hits the acid media of the stomach, it becomes oxidized into the ubiquinone form. But it is the lipid-soluble form of CoQ-10 that is needed to be absorbed by the intestines. Unaltered, natural ubiquinone as in Premier CoQ10 is preferred because it is in its original, fat-soluble state. Premier CoQ-10 offers your clients a wise choice in the selection of CoQ-10 present in its natural form to deliver the wide range of its famous benefits, including cardiovascular, nerve, brain and immune support.
PRL Technical Bulletin